SCHEMBL893216

SCHEMBL893216

CC(C)C(Cl)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
TAAR1 Q96RJ0 4/20 0.44
AOC3 Q16853 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41
CYP2D6 P10635 1/20 0.41
LMNA P02545 1/20 0.41
HIF1A Q16665 1/20 0.41
ALDH1A1 P00352 2/20 0.39
DPP4 P27487 2/20 0.39
F2 P00734 1/20 0.39
MIF P14174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL28777513 0.89 CYP2D6 (0.43) TSHRCYP2D6LMNAALDH1A1
SCHEMBL498588 0.83 TSHR (0.52) TSHRTAAR1KDM4EADRA2AADRA2C
SCHEMBL304645 0.83 TSHR (0.52) TSHRTAAR1KDM4EADRA2AADRA2C
SCHEMBL306112 0.83 TSHR (0.52) TSHRTAAR1KDM4EADRA2AADRA2C
SCHEMBL6283476 0.82 TSHR (0.65) TSHRTAAR1CYP2D6LMNADPP4
SCHEMBL9750479 0.81 TSHR (0.50) TSHRTAAR1KDM4EADRA2AADRA2C
SCHEMBL3280292 0.79 ADRA2A (0.54) TSHRTAAR1AOC3KDM4EADRA2A
SCHEMBL4778223 0.79 LMNA (0.48) TSHRAOC3KDM4EADRA2AADRA2C
SCHEMBL11887151 0.79 ADRA2A (0.54) TSHRTAAR1AOC3KDM4EADRA2A
Hydrochloric Acid SCHEMBL3284983 0.77 ALDH1A1 (0.56) TSHRTAAR1KDM4EADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof NORTHEASTERN UNIVERSITY (US) 2022-01-04 US disclosed
CN-107417890-B Composition, cured product, prepreg, and laminate 日铁化学材料株式会社 2021-07-20 CN disclosed
US-20200287140-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-09-10 US disclosed
US-20200148696-A1 Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof NORTHEASTERN UNIVERSITY 2020-05-14 US disclosed
US-10570146-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof NORTHEASTERN UNIVERSITY (US) 2020-02-25 US disclosed
US-20170247387-A1 UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF NORTHEASTERN UNIVERSITY 2017-08-31 US disclosed
CN-106220486-A A kind of synthetic method of high-load cyclamen aldehyde spice 安徽华业香料股份有限公司 2016-12-14 CN disclosed
CN-106187719-A The synthetic method of cyclamen aldehyde precursor p-isopropyl β chlorine α methylbenzene acrylic aldehyde 安徽华业香料股份有限公司 2016-12-07 CN disclosed
US-20160122450-A1 SYNTHESIS OF A SUBSTITUTED FURAN AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-05-05 US disclosed
WO-2016014975-A2 UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF NORTHEASTERN UNIVERSITY (US) 2016-01-28 WO disclosed
EP-0250090-A2 Storage stable latently curable acrylic formulations employing polymeric hydroperoxides LOCTITE CORPORATION (US) 1987-12-23 EP disclosed
US-4568761-A Process for preparing tertiary aralkyl carbamates from tertiary aralkyl chlorides AMERICAN CYANAMID COMPANY (US) 1986-02-04 US disclosed
EP-0074008-B1 PROCESS FOR PRODUCING ALPHA-ARYLALKANOIC ACID ESTERS TAISHO PHARMACEUTICAL CO. LTD (JP) 1984-10-10 EP disclosed
US-4452746-A TO MODIFY PROPERTIES OF HIGH MOLECULAR WEIGHT COMPOUNDS NIPPON PAINT CO., LTD. (JP) 1984-06-05 US disclosed
US-4433160-A Process for producing α-arylalkanoic acid ester TAISHO PHARMACEUTICAL COMPANY, LTD. (JP) 1984-02-21 US disclosed
EP-0074008-A2 Process for producing alpha-arylalkanoic acid esters TAISHO PHARMACEUTICAL CO. LTD (JP) 1983-03-16 EP disclosed
US-4352748-A Novel acyl-polyalkylindan compounds and the use thereof as a base for perfume, as well as perfume compositions NAARDEN INTERNATIONAL N.V. (NL) 1982-10-05 US disclosed
EP-0009077-B1 SUBSTITUTED PHENYLPROPYL HALIDES, THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1981-09-30 EP disclosed
EP-0009683-A1 Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions MERCK PATENT GmbH (DE) 1980-04-16 EP disclosed
US-4196151-A Process for producing β,γ-unsaturated aldehyde NIPPON OIL AND FATS CO., LTD. (JP) 1980-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214578-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof FAAH, FAAH2, MGLL TSHR 2828/4885TAAR1 537/4885AOC3 170/4885
US-20200287140-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF OR51E2, PIEZO1, OR10J3 TSHR 4618/4885TAAR1 2842/4885AOC3 187/4885
US-10570146-B2 Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof FAAH, FAAH2, MGLL TSHR 2380/4885TAAR1 430/4885AOC3 628/4885
US-20170247387-A1 UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF FAAH, FAAH2, MGLL TSHR 2518/4885TAAR1 718/4885AOC3 469/4885
US-20160122450-A1 SYNTHESIS OF A SUBSTITUTED FURAN DCXR, PFAS, FUT6 TSHR 2815/4885TAAR1 3296/4885AOC3 536/4885
US-20200148696-A1 Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof FAAH, MGLL, FAAH2 TSHR 2183/4885TAAR1 639/4885AOC3 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.