Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.34 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38658785 | 0.86 | MAGI3 (0.44) | RENDPP7MAPK8MAPK9MAPK10 | |
| SCHEMBL30242278 | 0.80 | MEN1 (0.42) | RENDPP7MAPK8MAPK9MAPK10 | |
| SCHEMBL38657878 | 0.79 | CALCRL (0.43) | RENDPP7MAPK8MAPK9MAPK10 | |
| SCHEMBL30496162 | 0.79 | MEN1 (0.42) | RENDPP7PRCP | |
| SCHEMBL29723375 | 0.78 | DPP7 (0.40) | RENDPP7MAPK8MAPK9MAPK10 | |
| SCHEMBL38658073 | 0.78 | CALCRL (0.45) | RENMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL31122253 | 0.78 | CALCRL (0.45) | RENDPP7MAPK8MAPK9MAPK10 | |
| SCHEMBL30658579 | 0.76 | ENPEP (0.47) | RENMAPK8MAPK9MAPK10 | |
| SCHEMBL30112831 | 0.76 | DPP7 (0.41) | RENDPP7KEAP1PRCP | |
| SCHEMBL30197893 | 0.76 | REN (0.42) | RENDPP7PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900238-B1 | HIV protease inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-05-31 | — | — | US | disclosed |