Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 7/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 7/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280391 | 1.00 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL6277897 | 0.79 | ADRA2A (0.65) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL12287584 | 0.79 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL6285589 | 0.79 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL16216183 | 0.76 | ADRA2A (0.61) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL5354526 | 0.74 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| SCHEMBL11951604 | 0.71 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CADRA1AHIF1A | |
| SCHEMBL13957533 | 0.71 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CALDH1A1LMNA | |
| Oxedrine SCHEMBL2283013 | 0.70 | KDM4E (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 | |
| Oxedrine SCHEMBL17726874 | 0.70 | KDM4E (1.00) | ADRA2AADRA2BADRA2CADRA1AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900203-B2 | Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them | POLIUM TECHNOLOGIES, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040002549-A1 | Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002549-A1 | Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them | ACHE, ALKBH3, BCHE | ADRA2A 1296/4885ADRA2B 944/4885ADRA2C 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.