Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662033 | 0.84 | THRB (0.38) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL285817 | 0.79 | THRB (0.38) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL285117 | 0.75 | THRB (0.50) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3169549 | 0.73 | CYP2C19 (0.46) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL285778 | 0.72 | THRB (0.47) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL30887689 | 0.71 | CYP2C19 (0.44) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4596471 | 0.71 | ALDH1A1 (0.48) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27856981 | 0.71 | CYP2C19 (0.44) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL285067 | 0.71 | TSHR (0.49) | THRBALDH1A1CYP3A4HIF1ATHRA | |
| SCHEMBL285105 | 0.71 | TSHR (0.49) | THRBALDH1A1CYP3A4HIF1ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6842288-B1 | Multilayer optical adhesives and articles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-11 | — | — | US | disclosed |