Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288924 | 0.87 | IGF1R (0.42) | IGF1RALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL6283894 | 0.85 | HTT (0.41) | IGF1RALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL6283927 | 0.85 | IGF1R (0.39) | IGF1RALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL5033203 | 0.84 | ADRB2 (0.43) | TLR8ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL5649980 | 0.82 | TLR8 (0.54) | IGF1RTLR8MCHR1ALDH1A1ADRB2 | |
| SCHEMBL3840437 | 0.81 | ADRB2 (0.41) | IGF1RALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL6286893 | 0.81 | ADRB2 (0.41) | IGF1RALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL60041 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL713645 | 0.77 | ALDH1A1 (0.46) | IGF1RALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL2098846 | 0.77 | HPGD (0.48) | TLR8MCHR1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040220342-A1 | Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part | YAMASHITA YUKIHIKO (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |