SCHEMBL6288924

SCHEMBL6288924

C=Cc1ccccc1OCC(C)CCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.42
ADRB2 P07550 4/20 0.39
ADRB1 P08588 4/20 0.39
LMNA P02545 3/20 0.39
CYP1A2 P05177 2/20 0.39
HTR1A P08908 2/20 0.39
CYP2D6 P10635 2/20 0.39
SLC6A4 P31645 2/20 0.39
ADRA1A P35348 2/20 0.39
SLC22A1 O15245 1/20 0.39
HTR2A P28223 1/20 0.39
TSHR P16473 2/20 0.37
ADRB3 P13945 1/20 0.37
ADRA2C P18825 1/20 0.37
SLC6A2 P23975 1/20 0.37
BDKRB2 P30411 1/20 0.37
HTR2B P41595 1/20 0.37
KCNH2 Q12809 1/20 0.37
NFKB1 P19838 1/20 0.37
GPR88 Q9GZN0 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6284579 0.87 IGF1R (0.53) IGF1RADRB2ADRB1LMNACYP1A2
SCHEMBL5033203 0.82 ADRB2 (0.43) ADRB2ADRB1LMNACYP1A2HTR1A
SCHEMBL6283894 0.79 HTT (0.41) IGF1RADRB2ADRB1LMNACYP1A2
SCHEMBL6283927 0.79 IGF1R (0.39) IGF1RADRB2ADRB1LMNACYP1A2
SCHEMBL3840437 0.79 ADRB2 (0.41) IGF1RADRB2ADRB1LMNACYP1A2
SCHEMBL6286893 0.79 ADRB2 (0.41) IGF1RADRB2ADRB1LMNACYP1A2
SCHEMBL2098846 0.78 HPGD (0.48) LMNACYP1A2TSHRHTR2BALDH1A1
SCHEMBL713645 0.78 ALDH1A1 (0.46) IGF1RLMNACYP1A2TSHRKDM4E
SCHEMBL6289176 0.77 HTT (0.51) TSHRKDM4ETDP1ALDH1A1HPGD
SCHEMBL406835 0.76 CYP1A2 (0.56) LMNACYP1A2TSHRHTR2BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6900273-B1 Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part HITACHI CHEMICAL CO., LTD. (JP) 2005-05-31 US disclosed
US-20040220342-A1 Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part YAMASHITA YUKIHIKO (JP) 2004-11-04 US disclosed
EP-1205517-A1 LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART HITACHI CHEMICAL COMPANY, LTD. (JP) 2002-05-15 EP disclosed