SCHEMBL6284665

SCHEMBL6284665

CCCCCCCCc1ccc(-c2ncc(O)cn2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.72
MAPT P10636 3/20 0.72
RAB9A P51151 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
HSD17B10 Q99714 3/20 0.72
KDM4E B2RXH2 2/20 0.72
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
USP2 O75604 1/20 0.72
GAA P10253 1/20 0.72
HPGD P15428 1/20 0.72
RARB P10826 6/20 0.62
ESR1 P03372 2/20 0.61
ADRA2A P08913 2/20 0.61
ADORA3 P0DMS8 2/20 0.61
TACR2 P21452 2/20 0.61
SLC6A2 P23975 2/20 0.61
SLC6A4 P31645 2/20 0.61
SLC6A3 Q01959 2/20 0.61
LMNA P02545 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080064 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL8020482 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL9550608 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL9817420 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL14062429 0.98 ALDH1A1 (0.70) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL6017875 0.98 ALDH1A1 (0.70) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL7881232 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL7090931 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL9252387 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL6253487 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005330204-A MEGAKARYOCYTE PRODUCTION-INDUCING AGENT OTSUKA PHARMACEUT CO LTD 2005-12-02 JP disclosed
EP-0606090-B1 Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KK (JP) 1997-10-29 EP disclosed
US-5589103-A Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1996-12-31 US disclosed
EP-0606090-A1 Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1994-07-13 EP disclosed
EP-0293763-B1 SMECTIC LIQUID CRYSTAL MIXTURE CHISSO CORPORATION (JP) 1992-07-29 EP disclosed
EP-0293764-B1 SMECTIC LIQUID CRYSTAL COMPOUND Chisso Corporation (JP) 1992-07-29 EP disclosed
US-5055221-A Rapidly switching ferroelectric display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed
US-4906400-A Smetic liquid crystal compound CHISSO CORPORATION (JP) 1990-03-06 US disclosed
EP-0224579-B1 SMECTIC LIQUID CRYSTALLINE PHASES MERCK PATENT GmbH (DE) 1990-01-24 EP disclosed
US-4882083-A CONTAINING OPTICALLY ACTIVE COMPOUND; HIGH SPEED RESPONSE DISPLAY ELEMENT CHISSO CORPORATION (JP) 1989-11-21 US disclosed
EP-0319167-A1 2-Phenyl-5-alkanoyloxypyrimidines Chisso Corporation (JP) 1989-06-07 EP disclosed
EP-0293764-A2 Smectic liquid crystal compound Chisso Corporation (JP) 1988-12-07 EP disclosed
EP-0293763-A2 Smectic liquid crystal mixture CHISSO CORPORATION (JP) 1988-12-07 EP disclosed
EP-0224579-A1 SMECTIC LIQUID CRYSTALLINE PHASES. MERCK PATENT GMBH (DE) 1987-06-10 EP disclosed
WO-1986007085-A1 SMECTIC LIQUID CRYSTALLINE PHASES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-12-04 WO disclosed