SCHEMBL9550608

SCHEMBL9550608

CCCCCCCc1ccc(-c2ncc(O)cn2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.72
MAPT P10636 3/20 0.72
RAB9A P51151 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
HSD17B10 Q99714 3/20 0.72
KDM4E B2RXH2 2/20 0.72
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
USP2 O75604 1/20 0.72
GAA P10253 1/20 0.72
HPGD P15428 1/20 0.72
RARB P10826 6/20 0.62
ESR1 P03372 2/20 0.61
ADRA2A P08913 2/20 0.61
ADORA3 P0DMS8 2/20 0.61
TACR2 P21452 2/20 0.61
SLC6A2 P23975 2/20 0.61
SLC6A4 P31645 2/20 0.61
SLC6A3 Q01959 2/20 0.61
LMNA P02545 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080064 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL6284665 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL8020482 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL9817420 1.00 ALDH1A1 (0.72) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL14062429 0.98 ALDH1A1 (0.70) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL6017875 0.98 ALDH1A1 (0.70) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL7881232 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL7090931 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL9252387 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10
SCHEMBL6253487 0.89 RAB9A (0.67) ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5201996-A None JP disclosed
JP-H05201996-A OPTICALLY ACTIVE CITRONELLOL DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME FUJI PHOTO FILM CO LTD 1993-08-10 JP disclosed
EP-0227717-B1 NITROGEN-CONTAINING HETEROCYCLIC ESTERS MERCK PATENT GmbH (DE) 1990-04-25 EP disclosed
US-4820839-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-04-11 US disclosed
EP-0227717-A1 NITROGEN-CONTAINING HETEROCYCLIC ESTERS. MERCK PATENT GMBH (DE) 1987-07-08 EP disclosed
WO-1986007055-A1 NITROGEN-CONTAINING HETEROCYCLIC ESTERS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-12-04 WO disclosed