SCHEMBL6284865

SCHEMBL6284865

CC(C)(c1ccc(Cc2ccccc2)cc1)C(C)(C)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.57
LTA4H P09960 3/20 0.50
LMNA P02545 2/20 0.47
CYP2D6 P10635 1/20 0.45
IDH1 O75874 1/20 0.43
SLC6A2 P23975 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
PLA2G10 O15496 1/20 0.42
PLA2G2A P14555 1/20 0.42
MAPK1 P28482 1/20 0.41
SLC22A2 O15244 1/20 0.41
TP53 P04637 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
IDO1 P14902 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3452699 0.86 CALM1 (0.57) CALM1LTA4HLMNACYP2D6IDH1
SCHEMBL548103 0.82 CALM1 (0.52) CALM1LTA4HLMNACYP2D6IDH1
SCHEMBL31465218 0.82 CALM1 (0.52) CALM1LTA4HLMNACYP2D6IDH1
SCHEMBL23641560 0.82 CALM1 (0.52) CALM1LTA4HLMNACYP2D6IDH1
SCHEMBL972712 0.79 CALM1 (0.92) CALM1LTA4HLMNAIDH1PLA2G10
SCHEMBL8094422 0.79 CALM1 (0.92) CALM1LTA4HLMNAIDH1PLA2G10
Bicarbonate SCHEMBL29057171 0.79 RAB9A (0.57) CALM1LMNAPLA2G10PLA2G2AMAPT
Diphenylmethane SCHEMBL9619576 0.78 CALM1 (0.60) CALM1LTA4HLMNACYP2D6SLC6A2
SCHEMBL5255445 0.76 ALDH1A1 (0.59) CALM1LTA4HTAAR1SMN1; SMN2IDO1
SCHEMBL6547275 0.76 CALM1 (0.57) CALM1LTA4HLMNACYP2D6IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
CN-103877703-A Dual-Core Comprising Zero Gradient Center And Positive Gradient Outer Core Layer ACUSHNET CO 2014-06-25 CN disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed