SCHEMBL6285263

SCHEMBL6285263

CCn1c2ccccc2c2cccc([N+](=O)[O-])c21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.57
KMT2A Q03164 6/20 0.57
LMNA P02545 4/20 0.57
MEN1 O00255 4/20 0.57
ALDH1A1 P00352 4/20 0.51
HTT P42858 2/20 0.51
NPC1 O15118 1/20 0.51
MITF O75030 1/20 0.51
AGTR1 P30556 1/20 0.51
RAB9A P51151 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TLR9 Q9NR96 1/20 0.51
PLK1 P53350 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29947976 1.00 MAPT (0.57) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL27936277 0.87 MAPT (0.68) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14292121 0.86 PGR (0.54) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL28864015 0.85 MAPT (0.69) MAPTKMT2ALMNAMEN1PLK1
SCHEMBL6285886 0.80 ALKBH5 (0.54) MAPTLMNAALDH1A1NPC1RAB9A
SCHEMBL5740655 0.79 KMT2A (0.56) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL27936304 0.78 MAPT (0.82) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL14208786 0.76 ALDH1A1 (0.59) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL15466547 0.76 ALDH1A1 (0.55) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL17885720 0.75 ALDH1A1 (0.53) MAPTKMT2ALMNAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974765-A Method for preparing 3-nitro-N-ethyl carbazole through microchannel reaction 安徽科芯微流化工科技有限公司 2023-04-18 CN disclosed
CN-115260085-A Preparation method of high-yield 3-nitro-9-ethyl carbazole 山西紫罗蓝新材料科技有限公司 2022-11-01 CN disclosed
CN-103254117-B A kind of method extracting nitration product from the nitrated solvent distillation residue of N-ethyl carbazole LONGXIANG CHEMICAL CO., LTD., NANTONG (CN) 2016-03-09 CN disclosed
CN-103254117-A Method for extracting nitration product from N-ethyl carbazole nitration solvent distillation residue NANTONG LONGXIANG CHEMICAL TECHNOLOGY CO LTD 2013-08-21 CN disclosed
US-6965037-B2 Method for producing aminocarbazoles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-11-15 US disclosed
US-20020183526-A1 Method for producing aminocarbazoles KAMIKAWA TAKASHI (JP) 2002-12-05 US disclosed
US-20010049448-A1 METHOD FOR PRODUCING AMINOCARBAZOLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-06 US disclosed