SCHEMBL6285498

SCHEMBL6285498

[c]1c(-c2ccccc2)cccc1C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 2/20 0.41
SENP7 Q9BQF6 2/20 0.41
SENP6 Q9GZR1 2/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPY5R Q15761 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KMO O15229 1/20 0.33
ADCY8 P40145 1/20 0.33
ADCY1 Q08828 1/20 0.33
ADORA3 P0DMS8 4/20 0.33
ADORA1 P30542 4/20 0.33
ADORA2A P29274 3/20 0.33
ADORA2B P29275 2/20 0.33
SLC18A3 Q16572 1/20 0.32
NR5A2 O00482 1/20 0.31
NR5A1 Q13285 1/20 0.31
CEL P19835 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1777152 0.80 CEL (0.38) CASP3SENP7SENP6POLBTDP1
SCHEMBL7949502 0.79 POLB (0.30) CASP3SENP7SENP6POLB
SCHEMBL21777712 0.78 CEL (0.36) CASP3SENP7SENP6POLBKMO
SCHEMBL17710524 0.74 CEL (0.32) KMOCEL
SCHEMBL28476729 0.72 CEL (0.33) CASP3SENP7SENP6POLBNPY5R
SCHEMBL1776322 0.72 CEL (0.33) CASP3SENP7SENP6POLBNPY5R
SCHEMBL27960979 0.72 ABCB1 (0.34) CASP3SENP7SENP6POLBKMO
SCHEMBL379055 0.71 ALDH1A1 (0.47) TDP1ALDH1A1
SCHEMBL4886658 0.69 CEL (0.32) CASP3SENP7SENP6KMOCEL
SCHEMBL1778508 0.69 CEL (0.32) KMOCEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102532030-A Synthesis method for multi-substituted 2-imidoimidazoline-4,5-diketone UNIV BEIJING 2012-07-04 CN disclosed
US-6929872-B2 Organic electroluminescent devices NIPPON STEEL CHEMICAL CO., LTD. (JP) 2005-08-16 US disclosed
US-20040028944-A1 Organic electroluminescent devices NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2004-02-12 US disclosed