SCHEMBL6285574

SCHEMBL6285574

Fc1[c]cc(F)c(-c2ccc(F)c(F)c2)c1F

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.34
IDO1 P14902 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17262624 0.77 MAOB (0.34) AKR1C3AKR1C2HSD17B1HSD17B2DHODH
SCHEMBL28123521 0.75 NOTUM (0.42) NOTUMIDO1AKR1C3AKR1C2CYP17A1
SCHEMBL12472411 0.72
SCHEMBL6735235 0.72 NOTUM (0.42) NOTUMIDO1AKR1C3AKR1C2CYP17A1
SCHEMBL6283639 0.71
SCHEMBL5798197 0.71 NOTUM (0.35) NOTUMAKR1C3AKR1C2CYP17A1CYP11B1
SCHEMBL16564208 0.69 NOTUM (0.34) NOTUMIDO1AKR1C3AKR1C2CYP17A1
SCHEMBL2724736 0.69 NOTUM (0.39) NOTUMIDO1AKR1C3AKR1C2CYP17A1
SCHEMBL13741967 0.68 CYP17A1 (0.52) NOTUMIDO1CYP17A1CYP11B1CYP11B2
SCHEMBL27554718 0.68 IDO1 (0.34) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1284626-C Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2006-11-15 CN disclosed
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
CN-1477995-A Fluorinated zwitterionic cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 NOTUM 213/4885IDO1 2554/4885AKR1C3 2633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.