Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287743 | 0.82 | KDM4E (0.31) | MEN1KMT2AMAPTHTTRAB9A | |
| SCHEMBL6286550 | 0.81 | MAPT (0.32) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6291007 | 0.78 | EPHX2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL6287860 | 0.77 | LTA4H (0.33) | RAB9A | |
| Hydrochloric Acid SCHEMBL6287926 | 0.75 | MAPT (0.45) | MEN1KMT2ATAAR1MAPTHTT | |
| Hydrochloric Acid SCHEMBL6291011 | 0.75 | LTA4H (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL7039294 | 0.73 | KLK1 (0.39) | MEN1KMT2AMAPTHTTRAB9A | |
| Trifluoroacetic Acid SCHEMBL6288018 | 0.73 | CES1 (0.39) | MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL6286281 | 0.73 | CES1 (0.39) | MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6290966 | 0.72 | L3MBTL1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | MEN1 111/4885KMT2A 2704/4885TAAR1 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.