Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PNLIP | P16233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7039294 | 0.88 | KLK1 (0.39) | KDM4EHPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL6286413 | 0.82 | MEN1 (0.31) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL6290435 | 0.78 | EGFR (0.34) | KLK1 | |
| SCHEMBL6290421 | 0.78 | EGFR (0.34) | KLK1 | |
| Trifluoroacetic Acid SCHEMBL6287794 | 0.77 | MLYCD (0.37) | MEN1LMNARAB9AKMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6290918 | 0.77 | MLYCD (0.37) | MEN1LMNARAB9AKMT2AHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6286326 | 0.77 | NR1H4 (0.37) | MEN1RAB9AKMT2AKLK1KLK5 | |
| SCHEMBL6287650 | 0.74 | CA1 (0.43) | MAPTLMNANPSR1 | |
| Trifluoroacetic Acid SCHEMBL6287884 | 0.73 | KEAP1 (0.37) | KDM4EHPGDMAPTMEN1RAB9A | |
| Trifluoroacetic Acid SCHEMBL7038495 | 0.73 | TP53 (0.35) | KDM4EHTTRAB9AKLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |