Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733375 | 0.75 | KDM4C (0.48) | EPHX1KDM4CKMT2AMEN1MMP1 | |
| SCHEMBL8237341 | 0.74 | KDM4C (0.47) | EPHX1KDM4CKMT2AMEN1MMP1 | |
| SCHEMBL5988047 | 0.73 | EPHX1 (0.50) | EPHX1KDM4CKMT2AMEN1MMP1 | |
| SCHEMBL25027534 | 0.72 | KDM4C (0.50) | EPHX1KDM4CKMT2AMEN1MMP1 | |
| SCHEMBL2293893 | 0.72 | KDM4C (0.48) | EPHX1KDM4CKMT2AMMP1MMP2 | |
| SCHEMBL24670688 | 0.70 | DNM1 (0.49) | EPHX1KDM4CCNR1CNR2ALDH1A1 | |
| SCHEMBL6285313 | 0.70 | TSHR (0.41) | KDM4CCNR1CNR2ALDH1A1 | |
| SCHEMBL993779 | 0.70 | EPHX1 (0.69) | EPHX1KDM4CKMT2AMEN1MMP1 | |
| SCHEMBL21779912 | 0.69 | EPHX1 (0.47) | EPHX1KDM4CKMT2AMEN1MMP1 | |
| SCHEMBL6286532 | 0.69 | KDM4C (0.43) | EPHX1KDM4CKMT2AMEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841703-B2 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1100772-B1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SC HOLDING AG (CH) | 2004-04-14 | — | — | EP | disclosed |
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| EP-1100772-A1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | Ciba SC Holding AG (CH) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007981-A1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | ALOX5, PTGER1, ALOX12 | EPHX1 174/4885KDM4C 668/4885KMT2A 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.