Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657880 | 0.96 | CYP4A11 (0.41) | CYP4A11RAB9ALOXL2CYP4F2FOLH1 | |
| SCHEMBL6000361 | 0.85 | FOLH1 (0.54) | CYP4A11RAB9ALOXL2CYP4F2FOLH1 | |
| SCHEMBL23792335 | 0.82 | LOXL2 (0.53) | CYP4A11RAB9ALOXL2CYP4F2CA1 | |
| SCHEMBL9442211 | 0.81 | FOLH1 (0.53) | CYP4A11RAB9ALOXL2CYP4F2FOLH1 | |
| SCHEMBL20168730 | 0.79 | CPA3 (0.46) | FOLH1CA1CA2CACNA1B | |
| SCHEMBL20179137 | 0.78 | FOLH1 (0.54) | FOLH1HDAC1HDAC6 | |
| SCHEMBL23582773 | 0.78 | LOXL2 (0.49) | CYP4A11LOXL2CYP4F2CA1CA2 | |
| SCHEMBL6000353 | 0.77 | CYP4A11 (0.49) | CYP4A11RAB9ALOXL2CYP4F2CA1 | |
| SCHEMBL28393119 | 0.77 | LOXL2 (0.51) | CYP4A11LOXL2CYP4F2CA1CA2 | |
| SCHEMBL6001848 | 0.76 | CYP4A11 (0.44) | CYP4A11RAB9ALOXL2CYP4F2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |