Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641130 | 0.88 | KMT2A (0.48) | NPC1MAPTRAB9ANPSR1PAX8 | |
| SCHEMBL5685794 | 0.88 | KMT2A (0.48) | NPC1MAPTRAB9ANPSR1PAX8 | |
| SCHEMBL989188 | 0.87 | KMT2A (0.66) | USP2TP53NPC1MAPTRAB9A | |
| SCHEMBL584940 | 0.84 | ALDH1A1 (0.55) | MAPTKMT2AALDH1A1GAATDP1 | |
| SCHEMBL29223025 | 0.83 | SMN1; SMN2 (0.48) | NPC1MAPTRAB9ANPSR1KMT2A | |
| SCHEMBL29222890 | 0.81 | PTGS2 (0.55) | MAPTKMT2AALDH1A1GAATDP1 | |
| SCHEMBL21980747 | 0.81 | CYP1A2 (0.42) | NPC1MAPTRAB9ANPSR1PAX8 | |
| Thiobenzoic Acid SCHEMBL21980749 | 0.81 | NPC1 (0.45) | NPC1MAPTRAB9ANPSR1PAX8 | |
| SCHEMBL28583492 | 0.79 | MAPT (0.57) | USP2TP53NPC1MAPTRAB9A | |
| SCHEMBL134091 | 0.78 | ALDH1A1 (0.59) | MAPTKMT2AALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |