Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286586 | 0.87 | USP2 (0.51) | KMT2AALDH1A1GAATDP1USP2 | |
| SCHEMBL9125693 | 0.84 | ALDH1A1 (0.62) | KMT2AALDH1A1GAATDP1MAPT | |
| SCHEMBL8945914 | 0.82 | ALDH1A1 (0.79) | KMT2AALDH1A1GAATDP1MAPT | |
| SCHEMBL18568766 | 0.81 | ALDH1A1 (0.72) | KMT2AALDH1A1GAATDP1NPC1 | |
| SCHEMBL27298687 | 0.80 | RAB9A (0.58) | KMT2AALDH1A1GAATDP1TP53 | |
| SCHEMBL438546 | 0.80 | ALDH1A1 (1.00) | KMT2AALDH1A1GAATDP1MAPT | |
| SCHEMBL29636490 | 0.80 | ALDH1A1 (1.00) | KMT2AALDH1A1GAATDP1MAPT | |
| SCHEMBL9042891 | 0.79 | LMNA (0.45) | KMT2AALDH1A1GAATDP1NPC1 | |
| Phenol SCHEMBL1068767 | 0.78 | ALDH1A1 (0.96) | KMT2AALDH1A1GAATDP1MAPT | |
| SCHEMBL1507640 | 0.78 | ALDH1A1 (0.96) | KMT2AALDH1A1GAATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803529-B1 | Solid phase sequencing of biopolymers | SEQUENOM, INC. (US) | 2010-09-28 | — | — | US | claimed |
| EP-0830460-A1 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996032504-A2 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-10-17 | — | — | WO | claimed |
| US-10441636-B2 | Method of diagnosis and treatment | LA TROBE UNIVERSITY (AU) | 2019-10-15 | — | — | US | disclosed |
| US-10376565-B2 | — | — | 2019-08-13 | — | — | US | disclosed |
| US-10344334-B2 | Method of diagnosing neoplasms | CLINICAL GENOMICS PTY. LTD. (AU) | 2019-07-09 | — | — | US | disclosed |
| EP-3056576-B1 | A METHOD OF DIAGNOSING NEOPLASMS | CLINICAL GENOMICS PTY LTD (AU) | 2019-02-13 | — | — | EP | disclosed |
| US-20190024188-A1 | METHOD OF DIAGNOSING NEOPLASMS - II | CLINICAL GENOMICS PTY. LTD. (AU) | 2019-01-24 | — | — | US | disclosed |
| EP-2874647-B1 | METHOD OF DIAGNOSIS AND TREATMENT OF METASTATIC CANCER | UNIV LA TROBE (AU) | 2018-10-24 | — | — | EP | disclosed |
| EP-2767595-B1 | Detection method for characterising the anatomical origin of a cell | CLINICAL GENOMICS PTY LTD (AU) | 2018-09-19 | — | — | EP | disclosed |
| EP-2644712-B1 | A method of diagnosing neoplasms - II | CLINICAL GENOMICS PTY LTD (AU) | 2018-07-04 | — | — | EP | disclosed |
| WO-2004058288-A1 | NOVEL THERAPEUTIC TARGETS IN CANCER | SAGRES DISCOVERY, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040126762-A1 | Novel compositions and methods in cancer | FORWARD VENTURES IV, L.P. | 2004-07-01 | — | — | US | disclosed |
| WO-2004033629-A2 | REVERSE TRANSCRIPTION ON MICROARRAYS | MERGEN LTD. (US) | 2004-04-22 | — | — | WO | disclosed |
| US-20040023267-A1 | Novel compositions and methods in cancer | LOTUS BIOSCIENCE INVESTMENT HOLDINGS LTD. (HK) | 2004-02-05 | — | — | US | disclosed |
| WO-2003080808-A2 | NOVEL COMPOSITIONS AND METHODS IN CANCER | SAGRES DISCOVERY, INC. (US) | 2003-10-02 | — | — | WO | disclosed |
| US-20030096258-A1 | Sequencing target nucleic acid; obtain single stranded nucleotide sequences, incubate with denatured nucleotide sequences, amplify determining sequence of nucleotide sequence | TRUSTEES OF BOSTON UNIVERSITY, THE | 2003-05-22 | — | — | US | disclosed |
| US-6436635-B1 | HYBRIDIZATION AND COMPLEXING WITH SINGLE-STRANDED NUCLEIC ACIDS; LIGATION TO PROBE; DISPLACEMENT POLYMERIZATION OF UNLIGATED STRAND; GENETIC ENGINEERING | BOSTON UNIVERSITY | 2002-08-20 | — | — | US | disclosed |
| EP-0830460-A1 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996032504-A2 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-10-17 | — | — | WO | disclosed |