Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001877 | 0.79 | LTB4R (0.42) | LTB4RLTB4R2PTGESALOX5PPARG | |
| Stearic Acid SCHEMBL8430838 | 0.74 | PTGER1 (0.53) | LTB4RLTB4R2PPARGPPARAMAPT | |
| SCHEMBL10741731 | 0.73 | CYSLTR2 (0.57) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL10741724 | 0.73 | CYSLTR2 (0.57) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL7013170 | 0.73 | FFAR1 (0.45) | LTB4RLTB4R2MAPTRXFP1S1PR1 | |
| SCHEMBL6001988 | 0.72 | LTB4R (0.49) | LTB4RLTB4R2MAPTRXFP1S1PR1 | |
| SCHEMBL6280250 | 0.72 | MAPT (0.52) | LTB4RLTB4R2MAPTRXFP1S1PR1 | |
| SCHEMBL6280253 | 0.72 | MAPT (0.52) | LTB4RLTB4R2MAPTRXFP1S1PR1 | |
| SCHEMBL4510764 | 0.72 | FFAR1 (0.43) | LTB4RLTB4R2PPARDMAPTRXFP1 | |
| SCHEMBL4510771 | 0.72 | FFAR1 (0.43) | LTB4RLTB4R2PPARDMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |