Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513248 | 0.71 | ALOX5 (0.39) | ALDH1A1GAAALOX5MAPTCYP1A2 | |
| SCHEMBL11757825 | 0.66 | SIGMAR1 (0.41) | ALDH1A1MAPTSMN1; SMN2TSHRMEN1 | |
| SCHEMBL10669247 | 0.64 | ALOX5 (0.38) | ALDH1A1GAAALOX5HSD17B10 | |
| SCHEMBL11795219 | 0.61 | NPSR1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL28901733 | 0.60 | CYP1A2 (0.48) | ALDH1A1MAPTCYP1A2TSHRKMT2A | |
| SCHEMBL548166 | 0.60 | CYP1A2 (0.54) | ALDH1A1MAPTCYP1A2TSHRKMT2A | |
| SCHEMBL9037033 | 0.59 | ALDH1A1 (0.58) | ALDH1A1GAAGPR6MAPTCYP1A2 | |
| SCHEMBL15376730 | 0.58 | CYP2C9 (0.47) | ALDH1A1MAPTCYP1A2TSHRL3MBTL1 | |
| SCHEMBL27596588 | 0.58 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP1A2TSHRMEN1 | |
| SCHEMBL507511 | 0.57 | NPSR1 (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005111020-A2 | PYRIMIDINE HYDANTOIN ANALOGUES WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2005-11-24 | — | — | WO | claimed |