SCHEMBL6286855

SCHEMBL6286855

Fc1ccc(C2=Cc3ccccc3C2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.53
CYP11B2 P19099 2/20 0.53
PTGS2 P35354 5/20 0.49
IP6K1 Q92551 1/20 0.43
IP6K3 Q96PC2 1/20 0.43
CYP19A1 P11511 1/20 0.40
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
PTAFR P25105 1/20 0.35
PRCP P42785 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
PTGS1 P23219 1/20 0.34
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31414397 1.00 CYP11B1 (0.53) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL11466575 0.85 CYP11B2 (0.56) CYP11B1CYP11B2PTGS2CYP19A1NISCH
SCHEMBL8058170 0.84 CYP11B2 (0.61) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL6285180 0.84 CYP11B2 (0.61) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL31608568 0.84 CYP11B2 (0.65) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL319265 0.84 CYP11B2 (0.65) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL30487694 0.82 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL6287169 0.82 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL31666281 0.82 CYP11B2 (0.62) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL25358298 0.81 CYP11B2 (0.53) CYP11B1CYP11B2PTGS2IP6K1IP6K3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1120182-C Thermoplastic elastic stereoblock olefin polymer, preparation method and metallocene catalyst UNIV LELAND STANFORD JUNIOR (US) 2003-09-03 CN claimed
US-6518378-B2 Using an unbridged cyclopentadienyl metallocene catalyst capable of interconverting between states with different copolymerization characteristics THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-02-11 US claimed
US-6479685-B2 POLYMERIZING ETHYLENE AND ANOTHER ALPHA-OLEFIN IN THE PRESENCE OF AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST COMPONENT AND A CO-CATALYST THE BOARD OF TRUSTEES OF THE LELAND STANDARD JUNIOR UNIVERSITY 2002-11-12 US claimed
US-20010049425-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-12-06 US claimed
US-20010034426-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-10-25 US claimed
US-6169151-B1 MADE BY POLYMERIZING ETHYLENE AND ALPHA-OLEFIN(S) USING AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST AND COCATALYST; CRYSTALLIZABLE ELASTOMERIC COPOLYMER PRODUCT HAS HIGHER MELTING POINT, NARROW COMPOSITION DISTRIBUTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2001-01-02 US claimed
US-6143842-A CONTINUOUSLY TRANSFERRING POLYOLEFIN, RESIDUAL CATALYST AND UNREACTED MONOMER TO CONDITIONING ZONE OF KNOWN VOLUME AND HEATING; CONTROLLING TRANSFER/REMOVAL OF POLYOLEFIN FROM THE ZONE TO ENABLE MONOMER REMOVAL WITHOUT OVERHEATING POLYOLEFIN HUNTSMAN POLYMERS CORPORATION (US) 2000-11-07 US claimed
WO-1999035171-A1 HIGH-MELTING POLYOLEFIN COPOLYMER ELASTOMERS, CATALYSTS AND METHODS OF SYNTHESIS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) 1999-07-15 WO claimed
EP-0802935-A4 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS UNIV LELAND STANFORD JUNIOR (US) 1998-09-30 EP claimed
CN-1172488-A Thermoplastic elastomeric stereoblock olefin polymers methods and metallocene catalysts TRUSTEES FO THE LELAND STANFOR (US) 1998-02-04 CN claimed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP claimed
US-5594080-A POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS LELAND STANFORD, JR. UNIVERSITY (US) 1997-01-14 US claimed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO claimed
US-20110049444-A1 COLORED RESIN COMPOSITIONS FOR COLOR FILTER, COLOR FILTER, ORGANIC EL DISPLAY, AND LIQUID-CRYSTAL DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-03-03 US disclosed
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US disclosed
US-20030195308-A1 Catalyst systems for high melting thermoplastic elastomeric alpha-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-10-16 US disclosed
CN-1147822-A Reactor blend polypropylene, process for the preparation thereof and process for preparing metallocene ligands MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-16 CN disclosed
EP-0745099-A1 REACTOR BLEND POLYPROPYLENE, PROCESS FOR THE PREPARATION THEREOF AND PROCESS FOR PREPARING METALLOCENE LIGANDS Montell Technology Company bv (NL) 1996-12-04 EP disclosed
WO-1996020225-A2 REACTOR BLEND POLYPROPYLENE, PROCESS FOR THE PREPARATION THEREOF AND PROCESS FOR PREPARING METALLOCENE LIGANDS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1996-07-04 WO disclosed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO disclosed