SCHEMBL6286922

SCHEMBL6286922

C=CCC(Cc1ccccc1)(C(=O)OCC)C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
RECQL P46063 1/20 0.52
MMP8 P22894 1/20 0.52
PIN1 Q13526 1/20 0.44
MAPK1 P28482 1/20 0.43
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
NPSR1 Q6W5P4 2/20 0.42
POLB P06746 1/20 0.42
PTPN1 P18031 3/20 0.41
PTPRC P08575 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
PPID Q08752 1/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 1/20 0.40
PTPN2 P17706 1/20 0.40
PTPRA P18433 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419400 0.86 ALDH1A1 (0.62) ALDH1A1RECQLMMP8PIN1NPSR1
SCHEMBL24872640 0.85 PTPRB (0.55) ALDH1A1RECQLMMP8CYP2C9CYP2C19
SCHEMBL7435532 0.83 ALDH1A1 (0.59) ALDH1A1RECQLMMP8PIN1NPSR1
SCHEMBL5916364 0.81 ALDH1A1 (0.57) ALDH1A1RECQLMMP8PIN1NPSR1
SCHEMBL7910569 0.81 MMP8 (0.43) ALDH1A1RECQLMMP8PIN1MAPK1
SCHEMBL163162 0.81 ALDH1A1 (0.54) ALDH1A1RECQLMMP8PIN1NPSR1
SCHEMBL17460412 0.80 ALDH1A1 (0.56) ALDH1A1RECQLMMP8PIN1CYP2C9
SCHEMBL24627654 0.79 ALDH1A1 (0.47) ALDH1A1MAPK1CYP3A4PTPN1PTPRC
SCHEMBL5661041 0.79 ALDH1A1 (0.55) ALDH1A1RECQLMMP8PIN1NPSR1
SCHEMBL10951249 0.79 ALDH1A1 (0.50) ALDH1A1RECQLMMP8PIN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60069055-A None JP disclosed
US-6867161-B1 Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-03-15 US disclosed
EP-0820809-A1 TITANIUM CATALYST, ORGANOTITANIUM REACTION REAGENT, PROCESSES FOR PRODUCING THESE, AND METHOD OF REACTION USING THESE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-01-28 EP disclosed
JP-S6069055-A 2-ALKYLINDANE-5-CARBOXYLIC ACID DERIVATIVE KANTO KAGAKU KK 1985-04-19 JP disclosed