Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563203 | 0.88 | LMNA (0.64) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL5332234 | 0.88 | TDP1 (0.60) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL26695099 | 0.86 | KMT2A (0.63) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL3497492 | 0.86 | KMT2A (0.58) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL31737534 | 0.86 | KMT2A (0.58) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL3919885 | 0.86 | KMT2A (0.58) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL1990848 | 0.85 | SLC6A2 (0.57) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL20482380 | 0.85 | KMT2A (0.57) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL2590133 | 0.84 | RAB9A (0.56) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL30901986 | 0.83 | TDP1 (0.54) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |