Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502601 | 0.81 | GPR84 (0.43) | TRIM24TRIM33ALDH1A1NPSR1MAPT | |
| SCHEMBL1255150 | 0.79 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1KDM4ENPC1 | |
| SCHEMBL7524895 | 0.79 | CYP1A2 (0.45) | TRIM24TRIM33ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9250621 | 0.78 | ALDH1A1 (0.59) | TRIM24TRIM33ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16152755 | 0.77 | KDR (0.47) | TRIM24TRIM33ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL805428 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL1584131 | 0.75 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1KDM4ENPC1 | |
| SCHEMBL12048608 | 0.73 | KDM4E (0.45) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL16334247 | 0.73 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL10834448 | 0.73 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032033-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2021-02-25 | — | — | WO | disclosed |
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |
| US-6426402-B1 | RESPIRATORY SYSTEM DISORDERS; RHEUMATIC DISEASES | SYNTEX (U.S.A.) LLC | 2002-07-30 | — | — | US | disclosed |