Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287767 | 0.81 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1MAPTNPSR1 | |
| SCHEMBL4822817 | 0.76 | GPR84 (0.45) | GPR84CHRM1CHRM2CHRM3PAK1 | |
| SCHEMBL2749556 | 0.75 | SMN1; SMN2 (0.63) | HAO1ALDH1A1 | |
| SCHEMBL9428564 | 0.75 | PTGS2 (0.52) | GPR84SOAT1 | |
| SCHEMBL9560125 | 0.75 | PTGS2 (0.52) | GPR84SOAT1 | |
| SCHEMBL7721146 | 0.75 | PTGS2 (0.52) | GPR84SOAT1 | |
| SCHEMBL11434977 | 0.75 | PTGS2 (0.52) | GPR84SOAT1 | |
| SCHEMBL1743341 | 0.75 | SMN1; SMN2 (0.42) | GPR84CHRM1PAK1ALDH1A1MAPT | |
| SCHEMBL11443812 | 0.75 | PTGS2 (0.52) | GPR84SOAT1 | |
| SCHEMBL9428037 | 0.75 | PTGS2 (0.52) | GPR84SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |