Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165708 | 0.86 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8002490 | 0.78 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL329825 | 0.73 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL3817963 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28534449 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4982471 | 0.69 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8002486 | 0.69 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL5177766 | 0.68 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9760116 | 0.68 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10071424 | 0.67 | TSHR (0.74) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897189-B2 | Anti-wrinkle silicone polysaccharide compounds and compositions comprising said compounds | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| EP-1461362-A1 | ANTI-WRINKLE SILICONE POLYSACCHARIDE COMPOUNDS AND COMPOSITIONS COMPRISING SAID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-29 | — | — | EP | disclosed |
| US-20030144169-A1 | Anti-wrinkle silicone polysaccharde compounds and compositions comprising said compounds | THE PROCTER & GAMBLE COMPANY | 2003-07-31 | — | — | US | disclosed |
| WO-2003050144-A1 | ANTI-WRINKLE SILICONE POLYSACCHARIDE COMPOUNDS AND COMPOSITIONS COMPRISING SAID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |