SCHEMBL8002490

SCHEMBL8002490

CC1(CCCOCC2CO2)CCC[Si](C)(C)O1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329825 0.81 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL6287842 0.78 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7165708 0.78 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8002486 0.74 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL16459205 0.73 TSHR (0.37) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL5177766 0.73 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4982471 0.72 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3817963 0.71 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28534449 0.71 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL9760116 0.70 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866522-A Special polyurea coating free of bottom coating for wooden loudspeaker box 青岛爱尔家佳新材料股份有限公司 2024-04-12 CN claimed
CN-113363458-B Preparation method of silicon-carbon negative electrode material 开封平煤新型炭材料科技有限公司 2022-11-15 CN claimed
CN-113363458-A Preparation method of silicon-carbon negative electrode material 开封平煤新型炭材料科技有限公司 2021-09-07 CN claimed
CN-110028763-B Preparation method of low-density high-rate epoxy resin microporous material 西北工业大学 2021-08-06 CN claimed
CN-117866522-A Special polyurea coating free of bottom coating for wooden loudspeaker box 青岛爱尔家佳新材料股份有限公司 2024-04-12 CN disclosed
CN-113861490-B Method for preparing epoxy microporous foam material based on liquid epoxy resin 西北工业大学 2022-12-23 CN disclosed
CN-113363458-B Preparation method of silicon-carbon negative electrode material 开封平煤新型炭材料科技有限公司 2022-11-15 CN disclosed
CN-113363458-A Preparation method of silicon-carbon negative electrode material 开封平煤新型炭材料科技有限公司 2021-09-07 CN disclosed
CN-110028763-B Preparation method of low-density high-rate epoxy resin microporous material 西北工业大学 2021-08-06 CN disclosed
CN-103410007-A Sol-gel pH discoloration finishing method for fabric UNIV DONGHUA 2013-11-27 CN disclosed
US-6013718-A ORGANOSILANE BONDING AGENT COUPLES SILICA FILLER TO THE DIENE POLYMER BEARING A SINGLE SILANOL FUNCTIONAL GROUP OR POLYSILOXANE BLOCK HAVING A SINGLE SILANOL END; REDUCED HYSTERESIS, USE AS A TIRE TREAD MICHELIN & CIE (FR) 2000-01-11 US disclosed
CN-1133318-A Thermo-insulating resin foam rising body and making method thereof MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1996-10-16 CN disclosed
EP-0545347-B1 Glass or quartz articles having high temperature resistant, UV absorbing coatings containing ceria PPG INDUSTRIES INC (US) 1995-03-08 EP disclosed
US-5316854-A Glass or quartz articles having high temperature UV absorbing coatings containing ceria PPG INDUSTRIES, INC. (US) 1994-05-31 US disclosed
EP-0545347-A1 Glass or quartz articles having high temperature resistant, UV absorbing coatings containing ceria PPG INDUSTRIES, INC. (US) 1993-06-09 EP disclosed