Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | Q9HBH1 | 1/20 | 0.48 | |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | CPA2 | P48052 | 1/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6290964 | 0.86 | KLKB1 (0.45) | CA1CA2KLKB1PDFPLG | |
| Hydrochloric Acid SCHEMBL6291010 | 0.85 | CALCRL (0.50) | CA1CA2KLKB1PDFPLG | |
| Hydrochloric Acid SCHEMBL6287855 | 0.85 | CALCRL (0.50) | CA1CA2KLKB1PDFPLG | |
| Hydrochloric Acid SCHEMBL6287982 | 0.84 | ROCK2 (0.45) | CA1CA2SIRT6SIRT1KLKB1 | |
| Hydrochloric Acid SCHEMBL6285953 | 0.84 | PLG (0.46) | CA1CA2KLKB1PDFPLG | |
| SCHEMBL7208633 | 0.83 | HDAC4 (0.53) | CA1CA2KLKB1PDFPLG | |
| SCHEMBL7210563 | 0.83 | HDAC4 (0.53) | CA1CA2KLKB1PDFPLG | |
| SCHEMBL21726052 | 0.83 | CA1 (0.51) | CA1CA2SIRT6SIRT1KLKB1 | |
| SCHEMBL21527195 | 0.83 | CA1 (0.54) | CA1CA2SIRT6SIRT1PDF | |
| SCHEMBL20303610 | 0.83 | PDF (0.69) | CA1CA2SIRT6SIRT1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |