Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.45 |
| ▸ | Q9HBH1 | 1/20 | 0.45 | |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | CPA2 | P48052 | 1/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418621 | 0.89 | KLKB1 (0.49) | CA1CA2KLKB1LTA4HSIRT1 | |
| SCHEMBL24774255 | 0.88 | LTA4H (0.49) | CA1CA2KLKB1LTA4HSIRT1 | |
| SCHEMBL21527195 | 0.83 | CA1 (0.54) | CA1CA2SIRT1PDFSIRT6 | |
| SCHEMBL15810600 | 0.83 | KLKB1 (0.43) | KLKB1LTA4HSIRT1PDFSSTR3 | |
| SCHEMBL6287948 | 0.83 | CA1 (0.49) | CA1CA2KLKB1SIRT1PDF | |
| SCHEMBL13411054 | 0.81 | SSTR3 (0.60) | LTA4HSSTR3MMP3 | |
| SCHEMBL24774073 | 0.80 | KLKB1 (0.44) | KLKB1LTA4HSIRT1PDFSSTR3 | |
| SCHEMBL16645118 | 0.79 | FURIN (0.47) | KLKB1LTA4HSIRT1PDFSSTR3 | |
| SCHEMBL20303610 | 0.79 | PDF (0.69) | CA1CA2KLKB1SIRT1PDF | |
| SCHEMBL20303609 | 0.79 | PDF (0.69) | CA1CA2KLKB1SIRT1PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10561738-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10561738-B2 | Immunoconjugates with an intracellularly-cleavable linkage | CD47, CD44, DNPEP | CA1 401/4885CA2 2076/4885KLKB1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.