Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FGB | P02675 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727652 | 0.91 | MEN1 (0.43) | MEN1KMT2AHSP90AA1HSP90AB1KDM4E | |
| SCHEMBL6274409 | 0.85 | MEN1 (0.55) | MEN1KMT2AHSP90AA1HSP90AB1KDM4E | |
| SCHEMBL4725463 | 0.84 | MEN1 (0.56) | MEN1KMT2AHSP90AA1HSP90AB1KDM4E | |
| SCHEMBL5084097 | 0.81 | MAOA (0.43) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL4726521 | 0.80 | MAOA (0.44) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL4729342 | 0.75 | PDE3B (0.39) | KDM4EALDH1A1RAB9ANSD2CASP6 | |
| SCHEMBL4726151 | 0.73 | PDE3B (0.40) | KDM4EALDH1A1TSHRRAB9ANSD2 | |
| SCHEMBL5083233 | 0.72 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1KDM4EALDH1A1MAPT | |
| SCHEMBL6268701 | 0.72 | MEN1 (0.49) | MEN1KMT2AHSP90AA1HSP90AB1KDM4E | |
| SCHEMBL4726086 | 0.71 | MEN1 (0.48) | MEN1KMT2AHSP90AA1HSP90AB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606263-A1 | RING-SUBSTITUTED 8-AMINOQUINOLINE DERIVATIVES AS ANTIMALARIAL AGENTS | Council of Scientific and Industrial Research (IN) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004085402-A1 | RING-SUBSTITUTED 8-AMINOQUNOLINE DERIVATES AS ANTIMALARIAL AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-07 | — | — | WO | disclosed |