Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 8/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 2/20 | 0.44 |
| ▸ | MC3R | P41968 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008370 | 0.81 | ICMT (0.81) | ICMTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL3262116 | 0.80 | MAPT (0.68) | ICMTNPSR1GAAALDH1A1HPGD | |
| SCHEMBL40822 | 0.80 | MAPT (0.68) | ICMTNPSR1GAAALDH1A1HPGD | |
| SCHEMBL29376364 | 0.80 | MAPT (0.68) | ICMTNPSR1GAAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL30295582 | 0.79 | MAPT (0.66) | ICMTNPSR1GAAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4598405 | 0.79 | MAPT (0.66) | ICMTNPSR1GAAALDH1A1HPGD | |
| SCHEMBL8299136 | 0.78 | HASPIN (0.46) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL2845034 | 0.78 | ICMT (0.61) | ICMTNPSR1GAAALDH1A1HPGD | |
| SCHEMBL6327060 | 0.78 | GPR84 (0.61) | ICMTNPSR1GAAALDH1A1HPGD | |
| SCHEMBL1032415 | 0.76 | NPSR1 (0.74) | ICMTNPSR1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930123-B2 | sPLA2 inhibitors | ELI LILLY AND COMPANY (US) | 2005-08-16 | — | — | US | disclosed |
| US-20040059130-A1 | Spla2 inhibitors | BEIGHT DOUGLAS WADE (US) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059130-A1 | Spla2 inhibitors | F2RL1, SPINT2, PLAAT2 | ICMT 4081/4885NPSR1 4090/4885GAA 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.