Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292349 | 0.89 | CTSK (0.45) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL8798293 | 0.81 | CTSK (0.54) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL26293714 | 0.78 | CTSK (0.52) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL1644719 | 0.78 | TP53 (0.53) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL3487855 | 0.78 | TP53 (0.53) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL3483760 | 0.78 | TP53 (0.53) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL7423041 | 0.78 | KMT2A (0.58) | ATMMEN1LMNAKMT2A | |
| SCHEMBL5898129 | 0.77 | CTSK (0.59) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL11982516 | 0.77 | CTSK (0.51) | CTSKCTSLCTSSCTSBATM | |
| SCHEMBL5325045 | 0.77 | CTSK (0.59) | CTSKCTSLCTSSCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849735-B1 | Methods of synthesis for 9-substituted hypoxanthine derivatives | MERCK EPROVA AG (CH) | 2005-02-01 | — | — | US | disclosed |