SCHEMBL8798293

SCHEMBL8798293

CC(NC(=O)OCc1ccccc1)C(=O)c1ccccc1N

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.54
CTSL P07711 3/20 0.52
CTSS P25774 3/20 0.52
CTSB P07858 1/20 0.52
ATM Q13315 1/20 0.51
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 1/20 0.50
ELANE P08246 1/20 0.48
CTRB1 P17538 2/20 0.48
TPSAB1 Q15661 2/20 0.47
PLG P00747 1/20 0.47
PRSS1 P07477 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9744407 0.84 CTSK (0.52) CTSKCTSLCTSSCTSBATM
SCHEMBL11019154 0.81 CTSK (0.49) CTSKCTSLCTSSCTSBATM
SCHEMBL6288544 0.81 CTSK (0.47) CTSKCTSLCTSSCTSBATM
SCHEMBL591895 0.80 CTSK (0.59) CTSKCTSLCTSSCTSBATM
SCHEMBL2627373 0.80 CTSK (0.59) CTSKCTSLCTSSCTSBATM
SCHEMBL591894 0.80 CTSK (0.59) CTSKCTSLCTSSCTSBATM
SCHEMBL15080869 0.80 CTSK (0.61) CTSKCTSLCTSSCTSBATM
SCHEMBL856196 0.80 CTSK (0.61) CTSKCTSLCTSSCTSBATM
SCHEMBL241565 0.80 CTSK (0.61) CTSKCTSLCTSSCTSBATM
SCHEMBL241564 0.80 CTSK (0.61) CTSKCTSLCTSSCTSBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0802915-A1 CAMPTOTHECIN DERIVATIVES AND ITS MANUFACTURING METHOD CHONG KUN DANG CORP (KR) 1997-10-29 EP disclosed