Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277779 | 0.92 | CA2 (0.59) | CA2CA1CA5ACA7CA9 | |
| SCHEMBL6277563 | 0.92 | CA2 (0.59) | CA2CA1CA5ACA7CA9 | |
| SCHEMBL6222747 | 0.92 | CA2 (0.59) | CA2CA1CA5ACA7CA9 | |
| SCHEMBL6285121 | 0.92 | CA2 (0.39) | CA2CA1ALDH1A1TSHRCA5A | |
| SCHEMBL6277726 | 0.92 | CA2 (0.39) | CA2CA1ALDH1A1TSHRCA5A | |
| SCHEMBL6171423 | 0.87 | — | — | |
| SCHEMBL18974594 | 0.79 | CA2 (0.55) | CA2CA1TSHRCA5ACA7 | |
| SCHEMBL6288712 | 0.78 | CA2 (0.38) | CA2ALDH1A1TSHR | |
| SCHEMBL668970 | 0.78 | — | — | |
| SCHEMBL9567053 | 0.78 | ALDH1A1 (0.45) | CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881755-B2 | N-(2-aryl-propionyl)-sulfonamides and pharmaceutical preparations containing them | Dompé S.p.A. (IT) | 2005-04-19 | — | — | US | disclosed |