Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288709 | 0.78 | CA2 (0.52) | CA2ALDH1A1TSHR | |
| SCHEMBL23868218 | 0.78 | CA2 (0.39) | CA2ALDH1A1KDM4E | |
| SCHEMBL12989475 | 0.77 | TSHR (0.43) | CA2ALDH1A1TSHRGAAKDM4E | |
| SCHEMBL16546828 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL | |
| SCHEMBL4512442 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL | |
| SCHEMBL316251 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL | |
| SCHEMBL5916068 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL | |
| SCHEMBL9567053 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL | |
| SCHEMBL21439801 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL | |
| SCHEMBL14770369 | 0.76 | ALDH1A1 (0.45) | CA2ALDH1A1TSHRKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881755-B2 | N-(2-aryl-propionyl)-sulfonamides and pharmaceutical preparations containing them | Dompé S.p.A. (IT) | 2005-04-19 | — | — | US | disclosed |