Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 2/20 | 0.51 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.45 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280784 | 1.00 | PTP4A3 (0.51) | PTP4A3PTP4A1ALDH1A1MAPTATM | |
| SCHEMBL10521426 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPTATMMEN1KMT2A | |
| SCHEMBL4662622 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPTATMMEN1KMT2A | |
| SCHEMBL4662620 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPTATMMEN1KMT2A | |
| SCHEMBL14603500 | 0.80 | POLB (0.47) | ALDH1A1MAPTATMMEN1KMT2A | |
| SCHEMBL29959844 | 0.80 | POLB (0.64) | ALDH1A1MAPTMEN1KMT2ASLC16A1 | |
| SCHEMBL7153194 | 0.80 | PTP4A3 (0.63) | PTP4A3PTP4A1ALDH1A1MAPTKMT2A | |
| SCHEMBL7153196 | 0.80 | PTP4A3 (0.63) | PTP4A3PTP4A1ALDH1A1MAPTKMT2A | |
| SCHEMBL13938656 | 0.80 | POLB (0.64) | ALDH1A1MAPTMEN1KMT2ASLC16A1 | |
| SCHEMBL4123656 | 0.80 | POLB (0.64) | ALDH1A1MAPTMEN1KMT2ASLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123664-A2 | PROCESSES FOR THE PREPARATION OF 2-CYANO-3-NAPHTHALENE-1-YL-ACRYLIC ACID ALKYL OR BENZYL ESTERS | WYETH (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277784-A1 | Processes for the preparation of 2-cyano-3-naphthalene-1-yl-acrylic acid alkyl or benzyl esters | WYETH (US) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277784-A1 | Processes for the preparation of 2-cyano-3-naphthalene-1-yl-acrylic acid alkyl or benzyl esters | TNF, ACACA, PCCA | PTP4A3 2284/4885PTP4A1 2813/4885ALDH1A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.