Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936335 | 1.00 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL11192910 | 0.81 | GRM2 (0.39) | ALDH1A1MAPTKDM4EMAPK1GRM2 | |
| SCHEMBL6288320 | 0.73 | MAPT (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27771891 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL5936329 | 0.64 | — | — | |
| SCHEMBL5936336 | 0.64 | — | — | |
| SCHEMBL24425855 | 0.64 | SMN1; SMN2 (0.41) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL11215643 | 0.63 | — | — | |
| SCHEMBL4014173 | 0.61 | BACE1 (0.39) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL28484432 | 0.61 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940781-A1 | LOADED BODY AND PHOTOELECTRIC CONVERSION ELEMENT | Adeka Corporation (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-6956055-B2 | Substituted γ-lactone compounds as NMDA-antagonists | GRUNENTHAL GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| US-4374249-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-02-15 | — | — | US | disclosed |