Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289176 | 0.91 | HTT (0.51) | HTTHPGDALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL7133337 | 0.89 | ALOX5 (0.43) | HTTHPGDALDH1A1SMN1; SMN2PPIA | |
| SCHEMBL19806810 | 0.83 | HTT (0.51) | HTTPPIANFKB1NFKB2RELA | |
| SCHEMBL3444287 | 0.83 | SMN1; SMN2 (0.41) | HTTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29378504 | 0.83 | ALDH1A1 (0.67) | HTTHPGDALDH1A1SMN1; SMN2PPIA | |
| SCHEMBL5033203 | 0.82 | ADRB2 (0.43) | HTTHPGDALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL3444430 | 0.82 | ALDH1A1 (0.44) | HTTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3793697 | 0.81 | ALDH1A1 (0.52) | HTTHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3445389 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AHTR1B | |
| SCHEMBL3445442 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040220342-A1 | Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part | YAMASHITA YUKIHIKO (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |