SCHEMBL6289573

SCHEMBL6289573

CCCCNC(C(CC)CCCC)C(CC)COC(=O)NC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.41
CA2 P00918 3/20 0.37
CA1 P00915 2/20 0.37
ALOX15 P16050 1/20 0.36
ACHE P22303 8/20 0.35
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP14 P50281 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5244752 0.90 EPHX1 (0.41) EPHX1CA2CA1ALOX15TSHR
SCHEMBL5244912 0.89 ACHE (0.49) EPHX1ALOX15ACHEMMP9MMP8
SCHEMBL5244825 0.88 ALOX15 (0.41) CA2CA1ALOX15ACHEMMP9
SCHEMBL5244887 0.87 EPHX1 (0.44) EPHX1CA2CA1ALOX15TSHR
SCHEMBL6287229 0.84 CA2 (0.38) CA2CA1ALOX15ACHETSHR
SCHEMBL5249428 0.82 ACHE (0.47) EPHX1ALOX15ACHEMMP9MMP8
SCHEMBL5246727 0.82 EPHX1 (0.41) EPHX1CA2CA1ALOX15ACHE
SCHEMBL5244774 0.81 ACHE (0.49) EPHX1ALOX15ACHEMMP9MMP8
SCHEMBL5246065 0.80 EPHX1 (0.45) EPHX1CA2CA1ALOX15TSHR
SCHEMBL6289689 0.76 EPHX1 (0.36) EPHX1CA2CA1MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed