Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096999 | 0.88 | TRPV1 (0.63) | EPHX2NR1H4TRPV1FPR2HPGD | |
| SCHEMBL22059470 | 0.80 | NR1H4 (1.00) | EPHX2NR1H4TRPV1MEN1MAPT | |
| SCHEMBL7877746 | 0.80 | EPHX2 (0.90) | EPHX2NR1H4TRPV1MAPTNPC1 | |
| SCHEMBL2657682 | 0.79 | NR1H4 (0.52) | EPHX2NR1H4MEN1MAPTKMT2A | |
| SCHEMBL14333684 | 0.79 | FPR2 (0.55) | EPHX2TRPV1CNR1MEN1MAPT | |
| SCHEMBL4092078 | 0.78 | TRPV1 (0.63) | EPHX2NR1H4TRPV1MEN1MAPT | |
| SCHEMBL14334007 | 0.78 | TRPM8 (0.68) | EPHX2TRPV1 | |
| SCHEMBL15021824 | 0.77 | TRPM8 (0.69) | TRPV1 | |
| SCHEMBL3873116 | 0.74 | NR1H4 (0.81) | EPHX2NR1H4TRPV1MEN1KMT2A | |
| SCHEMBL7297239 | 0.74 | NR1H4 (0.81) | EPHX2NR1H4TRPV1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953812-B2 | Glucagon antagonists/inverse agonists | NOVO NORDISK, INC. (DK) | 2005-10-11 | — | — | US | disclosed |