Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.59 |
| ▸ | MMP3 | P08254 | 10/20 | 0.59 |
| ▸ | MMP2 | P08253 | 9/20 | 0.59 |
| ▸ | MMP1 | P03956 | 8/20 | 0.59 |
| ▸ | MMP7 | P09237 | 6/20 | 0.59 |
| ▸ | MMP8 | P22894 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809660 | 0.97 | MMP13 (0.64) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL6294217 | 0.86 | MMP13 (0.55) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL6290466 | 0.85 | MMP13 (0.69) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7082697 | 0.84 | MMP13 (0.65) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7078213 | 0.83 | MMP13 (0.60) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7080925 | 0.83 | MMP13 (0.64) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7081077 | 0.81 | MMP13 (0.66) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7045752 | 0.80 | MMP13 (0.71) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7046221 | 0.79 | MMP13 (0.58) | MMP13MMP3MMP2MMP1MMP7 | |
| SCHEMBL7077489 | 0.78 | MMP13 (0.64) | MMP13MMP3MMP2MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949545-B2 | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2005-09-27 | — | — | US | disclosed |
| US-20030139414-A1 | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139414-A1 | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors | MME, MMP2, MMP9 | MMP13 38/4885MMP3 13/4885MMP2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.