Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285158 | 0.98 | KEAP1 (0.55) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL6287670 | 0.93 | KEAP1 (0.50) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL9547610 | 0.93 | EPHX1 (0.61) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL19171946 | 0.93 | EPHX1 (0.61) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL13466509 | 0.90 | KEAP1 (0.61) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL19171419 | 0.85 | EPHX1 (0.58) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL11382117 | 0.85 | KEAP1 (0.55) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL24285430 | 0.84 | EPHX1 (0.78) | EPHX1 | |
| SCHEMBL25228539 | 0.84 | EPHX1 (0.78) | EPHX1 | |
| SCHEMBL8397082 | 0.84 | EPHX1 (0.78) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |