Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171946 | 1.00 | EPHX1 (0.61) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL13466509 | 0.97 | KEAP1 (0.61) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL6289749 | 0.93 | EPHX1 (0.54) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL19171419 | 0.92 | EPHX1 (0.58) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL11382117 | 0.92 | KEAP1 (0.55) | EPHX1KEAP1NFE2L2KDM4EMAPK1 | |
| SCHEMBL25228539 | 0.91 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL25277323 | 0.91 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL8395449 | 0.91 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL24285430 | 0.91 | EPHX1 (0.78) | EPHX1CASP2 | |
| SCHEMBL8397082 | 0.91 | EPHX1 (0.78) | EPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157978-B1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO CHEM B V (NL) | 2021-08-11 | — | — | EP | disclosed |
| US-20170210736-A1 | PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2017-07-27 | — | — | US | disclosed |
| US-9202709-B2 | Polishing liquid for metal and polishing method using the same | FUJIFILM CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20100075500-A1 | Metal polishing slurry and chemical mechanical polishing method | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20090239380-A1 | POLISHING LIQUID FOR METAL AND POLISHING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090088361-A1 | CLEANING AGENT FOR SEMICONDUCTOR DEVICE AND CLEANING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-7261999-B2 | Photothermographic materials containing post-processing stabilizers | CARESTREAM HEALTH, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7261999-B2 | Photothermographic materials containing post-processing stabilizers | CARESTREAM HEALTH, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20070117053-A1 | Photothermographic materials containing post-processing stabilizers | EASTMAN KODAK COMPANY | 2007-05-24 | — | — | US | disclosed |
| US-20070117053-A1 | Photothermographic materials containing post-processing stabilizers | EASTMAN KODAK COMPANY | 2007-05-24 | — | — | US | disclosed |
| US-5194660-A | Processes for producing carbamates and isocyanates | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| US-4621149-A | PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0083096-A2 | Production of urethane compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088361-A1 | CLEANING AGENT FOR SEMICONDUCTOR DEVICE AND CLEANING METHOD USING THE SAME | AOC1, SPIN1, USP1 | EPHX1 913/4885KEAP1 2229/4885NFE2L2 2908/4885 |
| US-20170210736-A1 | PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL | NHERF1, SLC9A3, SLC26A3 | EPHX1 1422/4885KEAP1 1087/4885NFE2L2 1616/4885 |
| US-20100075500-A1 | Metal polishing slurry and chemical mechanical polishing method | NOX1, NOXO1, PIEZO1 | EPHX1 3670/4885KEAP1 2929/4885NFE2L2 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.