Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285158 | 0.95 | KEAP1 (0.55) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL6289749 | 0.93 | EPHX1 (0.54) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL11382117 | 0.92 | KEAP1 (0.55) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL11231320 | 0.90 | EPHX1 (0.54) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL13466509 | 0.87 | KEAP1 (0.61) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL6286750 | 0.85 | KEAP1 (0.43) | KEAP1NFE2L2EPHX1HSD17B10 | |
| SCHEMBL9547610 | 0.84 | EPHX1 (0.61) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL4545267 | 0.84 | — | — | |
| SCHEMBL19171946 | 0.84 | EPHX1 (0.61) | KEAP1NFE2L2EPHX1KDM4EMAPK1 | |
| SCHEMBL12522322 | 0.83 | KDM4E (0.61) | KEAP1NFE2L2EPHX1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |