Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 5/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198642 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL8144862 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL8145211 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL4856848 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL5425896 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL3875391 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL2198649 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL2297828 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL10325897 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 | |
| SCHEMBL10326063 | 1.00 | TLR4 (0.52) | TLR4PRKCAAKT1MAPK1GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050196342-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-09-08 | — | — | US | disclosed |
| US-20050031543-A1 | Microbubble-generating carbohydrate microparticles with an incorporated surfactant for enhanced echocardiographic imaging | AMERSHAM HEALTH AS | 2005-02-10 | — | — | US | disclosed |
| US-20030059373-A1 | Contrast agents | NYCOMED IMAGING AS | 2003-03-27 | — | — | US | disclosed |
| EP-0620744-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-04-12 | — | — | EP | disclosed |
| EP-0972527-A2 | Contrast agents containing carbohydrate particles and a surfactant | NYCOMED IMAGING AS (NO) | 2000-01-19 | — | — | EP | disclosed |
| US-5827502-A | COMPRISING A CARBOHYDRATE MIXED WITH A SURFACTANT AND A BIOCOMPATIBLE LOW-MOLECULAR-WEIGHT FLUORINATED HYDROCARBON AS GAS; DIAGNOSTIC ULTRASONIC AND MAGNETIC RESONANCE IMAGING | NYCOMED IMAGING AS (NO) | 1998-10-27 | — | — | US | disclosed |
| EP-0586524-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1997-04-23 | — | — | EP | disclosed |
| US-5569449-A | BIOTOLERABLE MATRIX IN ASSOCIATION WITH FLUORINATED GAS, STABILIZED BY PRESENCE OF CROSS-LINKING GROUPS ATTACHED TO MATRIX | NYCOMED IMAGING AS (NO) | 1996-10-29 | — | — | US | disclosed |
| US-5558857-A | ULTRASONIC | NYCOMED IMAGING AS (NO) | 1996-09-24 | — | — | US | disclosed |
| US-5558856-A | SULFUR HEXAFLUORIDE OR LOW MOLECULAR WEIGHT FLUOROCARBON | NYCOMED IMAGING AS (NO) | 1996-09-24 | — | — | US | disclosed |
| EP-0620744-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-10-26 | — | — | EP | disclosed |
| EP-0586524-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS. | HOLMES MICHAEL JOHN (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993013808-A2 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | HOLMES, MICHAEL, JOHN (GB) | 1993-07-22 | — | — | WO | disclosed |
| WO-1992021382-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | HOLMES, MICHAEL, JOHN (GB) | 1992-12-10 | — | — | WO | disclosed |