Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290855 | 0.95 | TLR8 (0.54) | PSMB5TLR8BCHESIGMAR1LMNA | |
| SCHEMBL6289604 | 0.93 | TLR8 (0.55) | PSMB5TLR8BCHESIGMAR1LMNA | |
| SCHEMBL8911558 | 0.84 | TLR8 (0.50) | PSMB5TLR8DHODHTSHR | |
| SCHEMBL11455070 | 0.84 | PDE10A (0.57) | PSMB5TLR8SIGMAR1PDE10ASKP2 | |
| SCHEMBL6283828 | 0.81 | NPC1 (0.59) | PSMB5TLR8LMNAHIF1A | |
| SCHEMBL21974580 | 0.81 | PSMB5 (0.47) | PSMB5TLR8BCHEPDE10ASKP2 | |
| SCHEMBL31593167 | 0.80 | SKP2 (0.55) | PSMB5BCHESIGMAR1SKP2LMNA | |
| SCHEMBL1537772 | 0.80 | SKP2 (0.55) | PSMB5BCHESIGMAR1SKP2LMNA | |
| SCHEMBL7822732 | 0.80 | NPC1 (0.61) | TLR8LMNAHIF1A | |
| SCHEMBL28065707 | 0.78 | TLR8 (0.53) | PSMB5TLR8PDE10AKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294776-A | Method for preparing symmetric dimer of nitrogen heterocyclic ring aromatic compound | UNIV LANZHOU | 2016-02-03 | — | — | CN | disclosed |
| US-6884477-B1 | Electroluminescence device using liquid crystal compound | CANON KABUSHIKI KAISHA (JP) | 2005-04-26 | — | — | US | disclosed |