Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822732 | 0.92 | NPC1 (0.61) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6289604 | 0.91 | TLR8 (0.55) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6283828 | 0.90 | NPC1 (0.59) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7823855 | 0.90 | CASP3 (0.61) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6290855 | 0.89 | TLR8 (0.54) | TLR8PSMB5HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8977263 | 0.89 | TLR8 (0.42) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7825130 | 0.88 | MAPT (0.53) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9618095 | 0.88 | MAPT (0.53) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7831287 | 0.87 | ESR1 (0.63) | TLR8MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7824457 | 0.86 | MAPT (0.53) | TLR8MAPTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5695684-A | Mesomorphic compound, liquid crystal composition containing the compound, liquid crystal device using the composition, liquid crystal apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0678509-A2 | Liquid crystal device, apparatus and display method using the composition | CANON KABUSHIKI KAISHA (JP) | 1995-10-25 | — | — | EP | disclosed |