Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | TACR2 | P21452 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822732 | 0.99 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL7831287 | 0.92 | ESR1 (0.63) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8911558 | 0.90 | TLR8 (0.50) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL6290855 | 0.85 | TLR8 (0.54) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL6289604 | 0.84 | TLR8 (0.55) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL7823855 | 0.83 | CASP3 (0.61) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL7825130 | 0.82 | MAPT (0.53) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9618095 | 0.82 | MAPT (0.53) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL6290229 | 0.81 | PSMB5 (0.52) | LMNAHIF1ATLR8PSMB5 | |
| SCHEMBL8977263 | 0.80 | TLR8 (0.42) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005330204-A | MEGAKARYOCYTE PRODUCTION-INDUCING AGENT | OTSUKA PHARMACEUT CO LTD | 2005-12-02 | — | — | JP | disclosed |