Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.71 |
| ▸ | AR | P10275 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 4/20 | 0.71 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Al-43 SCHEMBL7132239 | 0.91 | NR3C1 (0.85) | NR3C1ARPGRNR3C2 | |
| SCHEMBL6291610 | 0.87 | NR3C1 (0.67) | NR3C1ARPGR | |
| Al-43 SCHEMBL29364100 | 0.84 | NR3C1 (1.00) | NR3C1ARPGR | |
| Al-43 SCHEMBL4172433 | 0.84 | NR3C1 (1.00) | NR3C1ARPGR | |
| Al-43 SCHEMBL7110788 | 0.84 | NR3C1 (1.00) | NR3C1ARPGR | |
| SCHEMBL4171493 | 0.83 | NR3C1 (1.00) | NR3C1ARPGRNR3C2 | |
| SCHEMBL6290384 | 0.80 | NR3C1 (0.75) | NR3C1ARPGRNR3C2 | |
| SCHEMBL4182301 | 0.78 | NR3C1 (0.87) | NR3C1ARPGRNR3C2 | |
| SCHEMBL4165850 | 0.77 | NR3C1 (0.81) | NR3C1ARPGRNR3C2 | |
| SCHEMBL4165229 | 0.77 | NR3C1 (0.85) | NR3C1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951942-B2 | Glucocorticoid-selective anti-inflammatory agents | ABBOTT LABORATORIES (US) | 2005-10-04 | — | — | US | disclosed |