Al-43

Al-43

SCHEMBL29364100

C=CCC1Oc2cccc(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 20/20 1.00
▸ PGR P06401 6/20 1.00
▸ AR P10275 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Al-43 SCHEMBL4172433 1.00 NR3C1 (1.00) NR3C1PGRAR
Al-43 SCHEMBL7110788 1.00 NR3C1 (1.00) NR3C1PGRAR
Al-43 SCHEMBL7132239 0.93 NR3C1 (0.85) NR3C1PGRAR
SCHEMBL6294343 0.91 NR3C1 (1.00) NR3C1PGRAR
SCHEMBL4170535 0.91 NR3C1 (1.00) NR3C1PGRAR
SCHEMBL4172432 0.91 NR3C1 (1.00) NR3C1PGRAR
SCHEMBL4186130 0.91 NR3C1 (0.83) NR3C1PGRAR
SCHEMBL6291135 0.90 NR3C1 (1.00) NR3C1PGRAR
SCHEMBL4179264 0.90 NR3C1 (1.00) NR3C1PGRAR
SCHEMBL4170282 0.90 NR3C1 (1.00) NR3C1PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240366632-A1 METHODS FOR THE TREATMENT OF OCULAR ROSACEA Institut National de la Santé et de la Recherche Médicale (FR) 2024-11-07 — — US claimed
EP-4395785-A1 METHODS FOR THE TREATMENT OF OCULAR ROSACEA Inserm (Institut National de la Santé et de la Recherche Scientifique) (FR) 2024-07-10 — — EP claimed
CN-114318201-B Control method for molten pool zinc slag of aluminum zinc pot in continuous hot dip aluminum zinc plating production line 上海梅山钢铁股份有限公司 2024-01-05 — — CN claimed
CN-114316809-B Sealant for lithium battery and preparation method thereof 南亚新材料科技股份有限公司 2023-10-20 — — CN claimed
WO-2023031277-A1 METHODS FOR THE TREATMENT OF OCULAR ROSACEA INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-03-09 — — WO claimed
CN-114318201-A Control method of zinc slag in molten pool of aluminum-zinc pot of continuous hot-dip aluminum-zinc plating production line 上海梅山钢铁股份有限公司 2022-04-12 — — CN claimed
EP-4745209-A1 LAMINATE AND ELECTRICAL INSULATION SHEET FOR MOTORS Toray Industries, Inc. (JP) 2026-05-20 — — EP disclosed
US-12630752-B2 Epoxy resin adhesive for medical device and cured product of the same, and medical device member and medical device FUJIFILM CORPORATION (JP) 2026-05-19 — — US disclosed
EP-4725558-A2 IMMUNOABLATIVE THERAPIES AVM Biotechnology, LLC (US) 2026-04-15 — — EP disclosed
EP-4720182-A1 SILICONE ELASTOMER FOR DIELECTRIC ACTUATORS, HAVING PROLONGED SERVICE LIFE Wacker Chemie AG (DE) 2026-04-08 — — EP disclosed
EP-3860612-B1 IMMUNOABLATIVE THERAPIES AVM BIOTECHNOLOGY LLC (US) 2026-03-04 — — EP disclosed
US-20260035563-A1 POLYSILOXANE FILLER TREATING AGENT AND COMPOSITIONS PREPARED THEREWITH DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-05 — — US disclosed
US-20260015463-A1 POLYSILOXANE FILLER TREATING AGENT AND COMPOSITIONS PREPARED THEREWITH DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-15 — — US disclosed
CN-114318201-A Control method of zinc slag in molten pool of aluminum-zinc pot of continuous hot-dip aluminum-zinc plating production line 上海梅山钢铁股份有限公司 2022-04-12 — — CN disclosed
EP-3971235-A1 STABILIZED MATRIX-FILLED LIQUID RADIATION CURABLE RESIN COMPOSITIONS FOR ADDITIVE FABRICATION Covestro (Netherlands) B.V. (NL) 2022-03-23 — — EP disclosed
CN-114196303-A Intelligent power module and radiating fin for same 苏州赛伍应用技术股份有限公司 2022-03-18 — — CN disclosed
WO-2022051583-A1 MEDIUM- OR MACRO-CYCLIC BENZYL-SUBSTITUTED HETEROCYCLE DERIVATIVES AND THEIR USES AS OREXIN-2 RECEPTOR AGONISTS OREXIA THERAPEUTICS LIMITED (GB) 2022-03-10 — — WO disclosed
US-11253594-B2 Drug combinations for protecting against neuronal cell death UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-02-22 — — US disclosed
US-20220033553-A1 COMPOSITIONS AND ARTICLES FOR ADDITIVE FABRICATION AND METHODS OF USING THE SAME STRATASYS INC. 2022-02-03 — — US disclosed
CN-109503761-B Stable matrix-filled liquid radiation curable resin compositions for additive fabrication 科思创(荷兰)有限公司 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035563-A1 POLYSILOXANE FILLER TREATING AGENT AND COMPOSITIONS PREPARED THEREWITH H1-0, COL1A1, H1-2 NR3C1 90/4885PGR 527/4885AR 1089/4885
US-12630752-B2 Epoxy resin adhesive for medical device and cured product of the same, and medical device member and medical device PIEZO1, EED, SRM NR3C1 3890/4885PGR 385/4885AR 1720/4885
US-11253594-B2 Drug combinations for protecting against neuronal cell death NLN, CASP3, BAX NR3C1 2129/4885PGR 3691/4885AR 4565/4885
US-20260015463-A1 POLYSILOXANE FILLER TREATING AGENT AND COMPOSITIONS PREPARED THEREWITH H1-0, COL1A1, RER1 NR3C1 800/4885PGR 1764/4885AR 3654/4885
US-20240366632-A1 METHODS FOR THE TREATMENT OF OCULAR ROSACEA NR3C1, NR3C2, MC2R NR3C1 1/4885PGR 30/4885AR 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback